I’m currently going through a Uranus transit to my 6th house that will last until 2026. I find that personal experience means much more to me than cookie cutter descriptions, so here is what I have experienced personally:
Increased need for freedom at work
I actually got laid off my full time job when Uranus was transiting my 6th house, with an exact opposition to my natal Saturn in the 12th house. Saturn rules my 2nd house of finance and income, which makes sense given that my job was paying most of my bills.
Before I was let go, I was struggling to keep a good routine. I felt easily overwhelmed by daily tasks and demands, and resented having a boss and obligations. Being laid off was a bit of a relief, as if I was being set free to do something more authentic to me and my personal dreams.
Desire for self employment
During this transit, I developed a stronger desire to work on my own. Authority and expectations were difficult to handle, so a traditional work environment felt suffocating to me. While losing one’s job and steady income is not ideal, it can feel very freeing during this transit as well.
Since the lay off, I have been working on ways to make money on my own and build something on my own. I have a strong desire to work for myself and set my own routines.
Health issues
If you are stuck in a health rut, Uranus will turn your approach on its head. Uranus in the 6th house will force you to course correct by interrupting your health and diet routines with new approaches. A friend of mine found out she was pre diabetic during this transit, and has adopted a new and innovative diet that has helped her lose weight and heal herself.
Stress and digestive related disorders are common during this period as well. The sixth house rules the digestive system, so you might experience gastro issues when Uranus is here.
A sense of nervousness and anxiety has definitely taken hold of my during this cycle, especially when transiting Uranus made a square to my natal Mars. I feel stressed and overwhelmed at simple tasks and chores. My routine has been difficult to stick with due to some stress-induced insomnia and angst. The funny thing is I have very little stress in my life, yet I feel so stressed!
It is also common to visit new age practitioners or adopt ‘innovative’ was of dealing with whatever health issues pop up in this cycle. I saw about 4 naturopaths during this period, but found none of them helpful. I did, however, try out new diets and herbal treatments during this time.
Changes in your career or unexpected health issues are common during this transit given Uranus’ reputation for sudden, unexpected and revolutionary events.
If Uranus makes a hard aspect to a career related planet (like Saturn, Jupiter, Pluto, or the ruler of the 2nd/6th/10th houses) while transiting your 6th house, unexpected job changes (like a sudden layoff or change of boss) might be coming your way.
If Uranus makes a harmonious aspect to a career related planet (like Saturn, Jupiter, or the ruler of the 2nd/6th/10th houses) while transiting your 6th house, positive job changes might come into being, in form of a promotion or getting a better job.
Uranus in hard aspects to your 6th house ruler, and other planets, can bring changes to your health and routines. Harsh aspects can bring difficult health and routine problems, while harmonious aspects can bring positive changes to your health and routines.
Predict When Love Will Enter Your Life! 
Order my new Book Predict Love with Astrology